Quality Profile Evaluation of Topical Semi-Solid Systems with Ibuprofen
نویسندگان
چکیده
منابع مشابه
Evaluation of Toxicological Profile of Ibuprofen in Wistar Albino Rats
Ibuprofen is an effective, cheap, and frequently used non-steroidal anti-inflammatory drug. The present study investigated the doseand time-dependent effects of ibuprofen on hepatic, renal, and hematological functions in rats. Groups of rats (n=6) were given ibuprofen (20, 40 mgkg -1 day -1 ) for 7, 14 or 28 days; or vehicle (control), orally. Blood samples were obtained, and hematological indi...
متن کاملFormulation & Evaluation of Meloxicam Solid Dispersion Incorporated Topical Gels
Solid dispersion complexes of meloxicam were prepared by using cyclodextrins (BCD, HPBCD), PVP and urea by kneading method in different molar and weight ratios. The complexes were characterized by DSC and IR, suggested that no chemical interaction between drug and carrier. The solubility, dissolution and permeability was studied for prepared complexes. The solubility, dissolution and permeabili...
متن کاملEvaluation of topical ibuprofen cream in the treatment of acute ankle sprains.
One hundred patients who presented to the accident and emergency (A&E) department with an acute ankle sprain were entered into a study to determine the efficacy of topical ibuprofen cream by using a double-blind placebo controlled design in a single type of soft-tissue injury. The subjects were given either topical ibuprofen cream or a placebo cream in addition to the standard management of the...
متن کاملSafranal-loaded solid lipid nanoparticles: evaluation of sunscreen and moisturizing potential for topical applications
Objective(s): In the current study, sunscreen and moisturizing properties of solid lipid nanoparticle (SLN)-safranal formulations were evaluated. Materials and Methods:Series of SLN were prepared using glyceryl monostearate, Tween 80 and different amounts of safranal by high shear homogenization, and ultrasound and high-pressure homogenization (HPH) methods. SLN formulations were characterized ...
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ژورنال
عنوان ژورنال: Proceedings
سال: 2019
ISSN: 2504-3900
DOI: 10.3390/proceedings2019029069